Article
Integrated miRNA and mRNA expression profiling identifies novel targets and pathological mechanisms in autoimmune thyroid diseases.
EBioMedicine - 1 Dec 2019
Martínez-Hernández Rebeca, Serrano-Somavilla Ana, Ramos-Leví Ana, Sampedro-Nuñez Miguel, Lens-Pardo Alberto, Muñoz De Nova José Luis, Triviño Juan Carlos, González María Ujue, Torné Lorena, Casares-Arias Javier, Martín-Cófreces Noa B, Sánchez-Madrid Francisco, Marazuela Mónica
Abstract excerpt
BACKGROUND: The mechanisms underlying autoimmune thyroid disease (AITD) remain elusive. Identification of such mechanisms would reveal novel and/or better therapeutic targets. Here, we use integrated analysis of miRNAs and mRNAs expression profiling to identify potential therapeutic targets involved in the mechanisms underlying AITD. METHODS: miRNA and mRNA from twenty fresh-frozen thyroid tissues (15 from AITD...
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