Article
Streptococcus mutans isolated from children with severe-early childhood caries form higher levels of persisters.
Archives of oral biology - 1 Feb 2020
Bottner Aaron, He Richard Y, Sarbu Andrea, Nainar S M Hashim, Dufour Delphine, Gong Siew-Ging, Lévesque Céline M
Abstract excerpt
OBJECTIVES: Dental caries is the most common chronic infectious disease in children. Streptococcus mutans, the main cariogenic bacterial species, produces persisters, nongrowing dormant variants of regular cells associated with chronicity of diseases. We hypothesized that the recurrent nature of caries, particularly within populations with high-caries risk, is due partly to specific phenotypic features of S....
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