Article
Poor mother-offspring relationships in rats with Cacna1a mutation.
Experimental animals - 24 Apr 2020
Kawakami Nozomi, Kobayashi Kiyoka, Nishimura Ayumu, Ohmori Iori
Abstract excerpt
Homozygous Groggy dams, which carry a Cacna1a missense mutation, often show no interest in their offspring, leading to frequent offspring deaths due to lack of nurturing. The present study aimed to clarify whether the Cacna1a mutation contributes to impaired attachment behaviors between dam and offspring. The open field test showed that homozygous female rats exhibited markedly short travel distance, whereas no...
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