Article
Checkpoint Regulation of Nuclear Tos4 Defines S Phase Arrest in Fission Yeast.
G3 (Bethesda, Md.) - 7 Jan 2020
Kim Seong M, Tripathi Vishnu P, Shen Kuo-Fang, Forsburg Susan L
Abstract excerpt
From yeast to humans, the cell cycle is tightly controlled by regulatory networks that regulate cell proliferation and can be monitored by dynamic visual markers in living cells. We have observed S phase progression by monitoring nuclear accumulation of the FHA-containing DNA binding protein Tos4, which is expressed in the G1/S phase transition. We use Tos4 localization to distinguish three classes of DNA...
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