A Brief History of Mitochondrial Pathologies.

Abstract excerpt

The history of "mitochondrial pathologies", namely genetic pathologies affecting mitochondrial metabolism because of mutations in nuclear DNA-encoded genes for proteins active inside mitochondria or mutations in mitochondrial DNA-encoded genes, began in 1988. In that year, two different groups of researchers discovered, respectively, large-scale single deletions of mitochondrial DNA (mtDNA) in muscle biopsies...

Topics

• DNA, Mitochondrial
• History, 20th Century
• History, 21st Century
• Humans
• Mitochondria
• Mitochondrial Diseases
• Mitochondrial Proteins
• Mutation