Article
X-irradiation of developing hippocampal neurons causes changes in neuron population phenotypes, dendritic morphology and synaptic protein expression in surviving neurons at maturity.
Neuroscience research - 1 Nov 2020
Puspitasari Anggraeini, Yamazaki Hiroyuki, Kawamura Hidemasa, Nakano Takashi, Takahashi Akihisa, Shirao Tomoaki, Held Kathryn D
Abstract excerpt
The effects of X-irradiation on developing neurons and their functions are unclear. We used primary cultures of mouse hippocampal neurons to investigate the effects of X-irradiation on cell death in developing neurons by analyzing caspase-3, MAP2 and DAPI-labeled cells, and the phenotypes and function of surviving neurons, by examining GAD67-positive cells as a GABAergic marker, and the synaptic markers synapsin...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.