Article
Evaluation of PAP in EGFR Mutational Testing in Advanced NSCLC: a Comparative Study.
Clinical laboratory - 1 Nov 2019
Jinliang Chen, Yang Xu, Xiaoyan Xu, Yudong Su, Xinyue Wang, Zhaoting Meng, Li Lin, Ning Sun, Hua Guo, Dingzhi Huang, Lun Zhang, Peng Chen
Abstract excerpt
BACKGROUND: EGFR mutational testing is crucial for advanced non-squamous NSCLC. PAP is a sensitive and selective method to detect rare mutations. METHODS: Eighty-five patients with non-squamous NSCLC were enrolled in this study. A set of paired plasma samples from each patient were collected and detected by PAP and ARMS. RESULTS: Of 85 paired samples, 78.8% (67/85) presented the same mutational status by the two...
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