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Article

Mutations in Hypervariable Domain of Venezuelan Equine Encephalitis Virus nsP3 Protein Differentially Affect Viral Replication.

Journal of virology - 17 Jan 2020

Meshram Chetan D, Phillips Aaron T, Lukash Tetyana, Shiliaev Nikita, Frolova Elena I, Frolov Ilya

Abstract excerpt

Venezuelan equine encephalitis virus (VEEV) is one of the important human and animal pathogens. It forms replication enzyme complexes (RCs) containing viral nonstructural proteins (nsPs) that mediate the synthesis of virus-specific RNAs. The assembly and associated functions of RC also depend on the presence of a specific set of host proteins. Our study demonstrates that the hypervariable domain (HVD) of VEEV...

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Topics

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytoskeletal Proteins

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Share to Protein Interaction Domains and Motifs

Share to src Homology Domains

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Source

Open in PubMed Open full text

Identifiers

PMID: 31694937
DOI: 10.1128/JVI.01841-19
PMCID: PMC7000987

Genes

CD2AP
SH3KBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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