Article
Characterization of tumour mutation burden in patients with non-small cell lung cancer and interstitial lung disease.
Respirology (Carlton, Vic.) - 1 Aug 2020
Kobayashi Haruki, Serizawa Masakuni, Naito Tateaki, Konno Hayato, Kojima Hideaki, Mizuno Tetsuya, Isaka Mitsuhiro, Endo Masahiro, Nagashima Takeshi, Kusuhara Masatoshi, Urakami Kenichi, Ohshima Keiichi, Yamaguchi Ken, Ohde Yasuhisa, Takahashi Toshiaki
Abstract excerpt
BACKGROUND AND OBJECTIVE: The efficacy expectation of immune checkpoint inhibitors against NSCLC in patients with ILD seems to be high because these populations are supposed to have high TMB. However, information about the characterization of TMB in patients with NSCLC and ILD is limited. Therefore, this study aimed to evaluate TMB in samples of NSCLC with ILD and clarify factors that influence TMB values....
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