Article
KRAS mutation and abnormal expression of Cripto-1 as two potential candidate biomarkers for detection of colorectal cancer development.
Journal of cellular biochemistry - 1 Apr 2020
Igder Somayeh, Mohammadiasl Javad, Azadpour Shima, Mansouri Esrafil, Ashktorab Hassan, Mokarram Pooneh
Abstract excerpt
Colorectal cancer (CRC), regardless of standard procedures of treatment and screening, is still considered one of the deadliest cancers in the Western world, and in economically developed Asian countries, especially Iran. The current study was undertaken to investigate whether changes in the level of Cripto-1 (CR-1) expression and KRAS mutations have a cumulative effect on the onset and progression of CRC. Fifty...
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