Article
Selective whole genome amplification and sequencing of Coxiella burnetii directly from environmental samples.
Genomics - 1 Mar 2020
Cocking Jill Hager, Deberg Michael, Schupp Jim, Sahl Jason, Wiggins Kristin, Porty Ariel, Hornstra Heidie M, Hepp Crystal, Jardine Claire, Furstenau Tara N, Schulte-Hostedde Albrecht, Fofanov Viacheslav Y, Pearson Talima
Abstract excerpt
Whole genome sequencing (WGS) is a widely available, inexpensive means of providing a wealth of information about an organism's diversity and evolution. However, WGS for many pathogenic bacteria remain limited because they are difficult, slow and/or dangerous to culture. To avoid culturing, metagenomic sequencing can be performed directly on samples, but the sequencing effort required to characterize low...
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