Article
A Novel Claudinopathy Based on Claudin-10 Mutations.
International journal of molecular sciences - 30 Oct 2019
Milatz Susanne
Abstract excerpt
Claudins are key components of the tight junction, sealing the paracellular cleft or composing size-, charge- and water-selective paracellular channels. Claudin-10 occurs in two major isoforms, claudin-10a and claudin-10b, which constitute paracellular anion or cation channels, respectively. For several years after the discovery of claudin-10, its functional relevance in men has remained elusive. Within the past...
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