Article
Association study of AGO1 and AGO2 genes polymorphisms with recurrent pregnancy loss.
Scientific reports - 30 Oct 2019
Kim Young Ran, Ryu Chang Soo, Kim Jung Oh, An Hui Jeong, Cho Sung Hwan, Ahn Eun Hee, Kim Ji Hyang, Lee Woo Sik, Kim Nam Keun
Abstract excerpt
An Argonaute (AGO) protein within the RNA-induced silencing complex binds a microRNA, permitting the target mRNA to be silenced. We hypothesized that variations in AGO genes had the possibility including affected the miRNA function and associated with recurrent pregnancy loss (RPL) susceptibility. Especially, we were chosen the AGO1 (rs595961, rs636832) and AGO2 (rs2292779, rs4961280) polymorphisms because of...
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