Article
CX3CL1-CX3CR1 Axis: A New Player in Coeliac Disease Pathogenesis.
Nutrients - 23 Oct 2019
Fernández-Prieto Marta, Fernández-Aceñero María Jesús, López-Palacios Natalia, Bodas Andrés, Farrais Sergio, Cuevas David, Pascual Virginia, Cerón-Nieto M Ángeles, Horta-Herrera Saúl, Espino-Paisán Laura, Salazar Isabel, Núñez Concepción
Abstract excerpt
BACKGROUND: The CX3CL1-CX3CR1 axis has been related to numerous diseases. The aim of our study was to investigate its involvement in coeliac disease (CD) pathogenesis, particularly in the early phase of the disease. METHODS: We collected peripheral blood from CD patients and controls, enrolled in a 3-day gluten challenge, to study soluble CX3CL1, I-TAC and MIG by Luminex, CX3CL1 and CX3CR1 gene expression by...
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