Article
Annexin V expression on CD4+ T cells with regulatory function.
Immunology - 1 Feb 2020
Bollinger Anna-Lena, Bollinger Thomas, Rupp Jan, Shima Kensuke, Gross Natalie, Padayachy Laura, Chicheportiche Rachel, Puga Yung Gisella L, Seebach Jörg Dieter
Abstract excerpt
Regulatory T (Treg) cells induce immunologic tolerance by suppressing effector functions of conventional lymphocytes in the periphery. On the other hand, immune silencing is mediated by recognition of phosphatidylserine (PS) on apoptotic cells by phagocytes. Here we describe expression of the PS-binding protein Annexin V (ANXA5) in CD4+ CD25hi Treg cells at the mRNA and protein levels. CD4+ ANXA5+ T cells...
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