A functional role for the cancer disparity-linked genes, CRYβB2 and CRYβB2P1, in the promotion of breast cancer.

doi:10.1186/s13058-019-1191-3

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Article

A functional role for the cancer disparity-linked genes, CRYβB2 and CRYβB2P1, in the promotion of breast cancer.

Breast cancer research : BCR - 11 Sept 2019

Barrow Maya A, Martin Megan E, Coffey Alisha, Andrews Portia L, Jones Gieira S, Reaves Denise K, Parker Joel S, Troester Melissa A, Fleming Jodie M

Abstract excerpt

BACKGROUND: In the USA, the breast cancer mortality rate is 41% higher for African-American women than non-Hispanic White women. While numerous gene expression studies have classified biological features that vary by race and may contribute to poorer outcomes, few studies have experimentally tested these associations. CRYβB2 gene expression has drawn particular interest because of its association with overall...

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PMID: 31511085
DOI: 10.1186/s13058-019-1191-3
PMCID: PMC6739962

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