Article
A latent unknown clustering integrating multi-omics data (LUCID) with phenotypic traits.
Bioinformatics (Oxford, England) - 1 Feb 2020
Peng Cheng, Wang Jun, Asante Isaac, Louie Stan, Jin Ran, Chatzi Lida, Casey Graham, Thomas Duncan C, Conti David V
Abstract excerpt
MOTIVATION: Epidemiologic, clinical and translational studies are increasingly generating multiplatform omics data. Methods that can integrate across multiple high-dimensional data types while accounting for differential patterns are critical for uncovering novel associations and underlying relevant subgroups. RESULTS: We propose an integrative model to estimate latent unknown clusters (LUCID) aiming to both...
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