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Orthostatic hypotension in hereditary transthyretin amyloidosis: epidemiology, diagnosis and management

26 Aug 2019

Abstract excerpt

PURPOSE: Neurogenic orthostatic hypotension is a prominent and disabling manifestation of autonomic dysfunction in patients with hereditary transthyretin (TTR) amyloidosis affecting an estimated 40-60% of patients, and reducing their quality of life. We reviewed the epidemiology and pathophysiology of neurogenic orthostatic hypotension in patients with hereditary TTR amyloidosis, summarize non-pharmacologic and...

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PMID: 31452021
DOI: 10.1007/s10286-019-00623-x

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