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Article

Acute Myeloid Leukemia: from Mutation Profiling to Treatment Decisions.

Current hematologic malignancy reports - 1 Oct 2019

DiNardo Courtney, Lachowiez Curtis

Abstract excerpt

PURPOSE OF REVIEW: Awareness of the molecular landscape of AML has improved AML care over the last 5 years. This review summarizes updates regarding the diagnostic and therapeutic relevance of key mutations in AML. RECENT FINDINGS: Molecular mutations in genes including NPM1, CEBPA, FLT3, IDH1/2, TP53, RUNX1, and ASXL1 provide important prognostic and/or therapeutic information in AML, including best treatment...

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Identifiers

PMID: 31350639
DOI: 10.1007/s11899-019-00535-7

Genes

FLT3
IDH1
ASXL1
NPM1
RUNX1
TP53

Provenance

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