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Article

Viral targeting of PDZ polarity proteins in the immune system as a potential evasion mechanism

23 Jul 2019

Abstract excerpt

PDZ proteins are highly conserved through evolution; the principal function of this large family of proteins is to assemble protein complexes that are involved in many cellular processes, such as cell-cell junctions, cell polarity, recycling, or trafficking. Many PDZ proteins that have been identified as targets of viral pathogens by promoting viral replication and spread are also involved in epithelial cell...

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PMID: 31336050
DOI: 10.1096/fj.201900518r

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