Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cdk5: A main culprit in neurodegeneration

22 Jul 2019

Abstract excerpt

Objectives: Neurodegenerative diseases (NDs) such as Alzheimer Diseases (AD), Parkinson Diseases (PD) are a huge public health problem. The elucidation of their pathophysiological mechanism is one of our greatest challenges. Hyperactive immune system contributes to the pathophysiology of neurological disorders.Methods: In this review article, we have highlighted the neurodegenerative role of CDK5 and its...

Topics

Join the communities discussing this publication.

Alzheimer's disease research and treatments
Autophagy in Disease and Therapy
Tryptophan and brain disorders

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 31327290
DOI: 10.1080/00207454.2019.1645142

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cdk5: A main culprit in neurodegenerationPMID 31327290Read ↗

Cdk5: a multifaceted kinase in neurodegenerative diseasesSemantic proximity Read ↗

Physiological and Pathological Roles of Cdk5: Potential Directions for Therapeutic Targeting in Neurodegenerative DiseaseSemantic proximity Read ↗

CDK5: A Unique CDK and Its Multiple Roles in the Nervous SystemSemantic proximity Read ↗

Cyclin-dependent Kinase 5 and Neurodegenerative DiseasesSemantic proximity Read ↗

Cdk5 Is a Key Factor in Tau Aggregation and Tangle Formation In VivoSemantic proximity Read ↗

CDK5 mediated phosphorylation of cytosolic phospholipase A2 regulates its activity and neuroinflammation in Parkinson’s DiseaseSemantic proximity Read ↗

Neuronal CDK7 in hippocampus is related to aging and Alzheimer diseaseSemantic proximity Read ↗

CDK5: Insights into its roles in diseasesSemantic proximity Read ↗

Protein Kinases and Neurodegenerative DiseasesSemantic proximity Read ↗

Hyperactive Innate Immunity Causes Degeneration of Dopamine Neurons upon Altering Activity of Cdk5Semantic proximity Read ↗

Probing the functions of microglial cyclin-dependent kinase 5 under physiological and pathological conditionsSemantic proximity Read ↗

Hyperactive Innate Immunity Causes Degeneration of Dopamine Neurons upon Altering Activity of Cdk5Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.