Article
RNA sequencing analysis revealed the induction of CCL3 expression in human intracranial aneurysms
17 Jul 2019
Abstract excerpt
Intracranial aneurysm (IA) is a socially important disease as a major cause of subarachnoid hemorrhage. Recent experimental studies mainly using animal models have revealed a crucial role of macrophage-mediated chronic inflammatory responses in its pathogenesis. However, as findings from comprehensive analysis of unruptured human IAs are limited, factors regulating progression and rupture of IAs in humans remain...
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