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Article

MicroRNA-486-3p functions as a tumor suppressor in oral cancer by targeting DDR1

28 Jun 2019

Abstract excerpt

BACKGROUND: Discoidin domain receptor-1 (DDR1) tyrosine kinase is highly expressed in a variety of human cancers and involved in various steps of tumorigenesis. However, the precise mechanisms underlying the abnormal expression of DDR1 in oral squamous cell carcinoma (OSCC) has not been well investigated. METHODS: The expression of DDR1 on OSCC patients was determine by quantitative real-time PCR (qRT-PCR) and...

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PMID: 31253192
DOI: 10.1186/s13046-019-1283-z

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