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Comparison of Illumina 450K and EPIC arrays in placental DNA methylation

28 Jun 2019

Abstract excerpt

Illumina HumanMethylation450 BeadChip (450K) has been commonly used to investigate DNA methylation in human tissues. Recently, it has been replaced by Illumina HumanMethylationEPIC BeadChip (EPIC) covering over 850,000 CpGs distributed genome-wide. Many consortia have now datasets coming from both arrays and aspire to analyze the two together. The placenta shows a high number of intermediate methylation levels...

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PMID: 31250700
DOI: 10.1080/15592294.2019.1634975

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