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Novel insights into endogenous RNA viral elements in Ixodes scapularis and other arbovirus vector genomes

1 Jan 2019

Abstract excerpt

Many emerging arboviruses are not transmitted by traditional mosquito vectors, but by lesser-studied arthropods such as ticks, midges, and sand flies. Small RNA (sRNA) silencing pathways are the main antiviral defence mechanism for arthropods, which lack adaptive immunity. Non-retroviral integrated RNA virus sequences (NIRVS) are one potential source of sRNAs which comprise these pathways. NIRVS are remnants of...

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PMID: 31249694
DOI: 10.1093/ve/vez010

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