Article
Frequency of Hepatitis B Virus Resistance Mutations in Women Using Tenofovir Gel as Pre-Exposure Prophylaxis.
Viruses - 19 Jun 2019
Baxter Cheryl, Ngcapu Sinaye, Blackard Jason T, Powell Eleanor A, Penton Patricia K, Abdool Karim Salim S
Abstract excerpt
Intermittent use of a single antiretroviral agent in the presence of a replicating virus could potentially increase the development of antiviral resistance. The pericoital, before-and-after sex, dosing regimen used in the Centre for the AIDS Programme of Research in South Africa (CAPRISA) 004 tenofovir gel trial meant that women who were infected with hepatitis B virus (HBV) were exposed intermittently to...
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