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VEGF – Supplemented extracellular matrix is sufficient to induce endothelial differentiation of human iPSC

18 Jun 2019

Abstract excerpt

Extracellular matrix (ECM) provides a scaffold for cells and tissues, but also supports organogenesis and tissue remodeling. The required instructive properties of the ECM to interact with cells depend on matrix architecture, structural proteins and functional matrix components such as growth factors, providing spatial, chemical and functional cues. Decellularized ECM (dECM) has been proposed as an instructive...

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PMID: 31247481
DOI: 10.1016/j.biomaterials.2019.119283

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