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Article

Juvenile idiopathic arthritis associated with a mutation in GATA3.

Arthritis research & therapy - 25 Jun 2019

Patrick Anna E, Wang Wei, Brokamp Elly, Graham Thomas Brent, Aune Thomas M, Duis Jessica B

Abstract excerpt

BACKGROUND: GATA3 is a transcription factor that is important during development and plays a role in differentiation and activity of immune cells, particularly T cells. Abnormal T cell function is found in autoimmune arthritis. We present the first known case of autoimmune arthritis associated with a novel GATA3 mutation. METHODS: Whole exome sequencing of the proband was performed on a clinical basis. Peripheral...

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Source

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Identifiers

PMID: 31238969
DOI: 10.1186/s13075-019-1946-3
PMCID: PMC6593533

Genes

GATA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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