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Countering the Modern Metabolic Disease Rampage With Ancestral Endocannabinoid System Alignment

17 May 2019

Abstract excerpt

When primitive vertebrates evolved from ancestral members of the animal kingdom and acquired complex locomotive and neurological toolsets, a constant supply of energy became necessary for their continued survival. To help fulfill this need, the endocannabinoid (eCB) system transformed drastically with the addition of the cannabinoid-1 receptor (CB1R) to its gene repertoire. This established an eCB/CB1R signaling...

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PMID: 31156558
DOI: 10.3389/fendo.2019.00311

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