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Overexpression of IGFBP2 mRNA predicts poor survival in patients with glioblastoma

28 May 2019

Abstract excerpt

Abstract The prognosis of patients with glioblastoma (GBM) is dismal. It has been reported that Insulin-like growth factor (IGF) binding protein 2 (IGFBP2) is associated with the mobility and invasion of tumor cells. We investigated the expression of IGFBP2 mRNA in GBMs and its clinical relevance, using tissue microarrays and RNAscope in situ hybridization in 180 GBMs and 13 normal or edematous tissues. The...

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PMID: 31138764
DOI: 10.1042/bsr20190045

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