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miR-146b level and variants is associated with endometriosis related macrophages phenotype and plays a pivotal role in the endometriotic pain symptom

1 May 2019

Abstract excerpt

OBJECTIVE: The aim of this study was to explore the effect of miR-146b expression and variants on endometriosis and its associated pain symptom. MATERIALS AND METHODS: Genotyping and expression of miR-146b was performed on 74 endometriosis patients and 23 healthy controls. ESCs were subsequently co-cultured with peripheral blood (PB)-derived monocytes (PBMC)-driven macrophages. After overexpression and inhibition...

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PMID: 31122533
DOI: 10.1016/j.tjog.2018.12.003

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