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Article

Small molecule targeting of RNA structures in neurological disorders

9 Apr 2019

Abstract excerpt

Aberrant RNA structure and function operate in neurological disease progression and severity. As RNA contributes to disease pathology in a complex fashion, that is, via various mechanisms, it has become an attractive therapeutic target for small molecules and oligonucleotides. In this review, we discuss the identification of RNA structures that cause or contribute to neurological diseases as well as recent...

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PMID: 30964958
DOI: 10.1111/nyas.14051

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