Article
Baseline identification of clonal V(D)J sequences for DNA-based minimal residual disease detection in multiple myeloma
22 Mar 2019
Abstract excerpt
Tracking of clonal immunoglobulin V(D)J rearrangement sequences by next generation sequencing is highly sensitive for minimal residual disease in multiple myeloma. However, previous studies have found variable rates of V(D)J sequence identification at baseline, which could limit tracking. Here, we aimed to define the factors influencing the identification of clonal V(D)J sequences. Bone marrow mononuclear cells...
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