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Modification of T2 phage infectivity towardEscherichia coliO157:H7 via using CRISPR/Cas9

1 Feb 2019

Abstract excerpt

Phage therapy is getting considerable attention as a method for prophylaxis of food poisoning caused by Escherichia coli O157:H7, an important pathogen causing life-threatening bloody diarrhea. Despite previous studies have shown the feasibility of phage therapy to E. coli O157:H7, promising results have not been obtained in vivo yet. A major drawback of phage therapy is that bacteriophages have high specificity...

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PMID: 30801649
DOI: 10.1093/femsle/fnz041

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