Article
Vasoactive intestinal peptide shapes first‐trimester placenta trophoblast, vascular, and immune cell cooperation
6 Feb 2019
Abstract excerpt
BACKGROUND AND PURPOSE: Extravillous trophoblast (EVT) cells are responsible for decidual stromal invasion, vascular transformation, and the recruitment and functional modulation of maternal leukocytes in the first-trimester pregnant uterus. An early disruption of EVT function leads to placental insufficiency underlying pregnancy complications such as preeclampsia and fetal growth restriction. Vasoactive...
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