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Article

Transcriptomic response of primary human airway epithelial cells to flavoring chemicals in electronic cigarettes

1 Feb 2019

Abstract excerpt

The widespread use of electronic cigarettes (e-cigarettes or e-cig) is a growing public health concern. Diacetyl and its chemical cousin 2,3-pentanedione are commonly used to add flavors to e-cig; however, little is known about how the flavoring chemicals may impair lung function. Here we report that the flavoring chemicals induce transcriptomic changes and perturb cilia function in the airway epithelium. Using...

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PMID: 30710127
DOI: 10.1038/s41598-018-37913-9

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