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Rapid detection of Mycobacterium ulcerans with isothermal recombinase polymerase amplification assay

1 Feb 2019

Abstract excerpt

BACKGROUND: Access to an accurate diagnostic test for Buruli ulcer (BU) is a research priority according to the World Health Organization. Nucleic acid amplification of insertion sequence IS2404 by polymerase chain reaction (PCR) is the most sensitive and specific method to detect Mycobacterium ulcerans (M. ulcerans), the causative agent of BU. However, PCR is not always available in endemic communities in Africa...

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PMID: 30707706
DOI: 10.1371/journal.pntd.0007155

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