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New insights into culture negative endophthalmitis by unbiased next generation sequencing

29 Jan 2019

Abstract excerpt

The proof-of-concept, study to investigate the presence of microorganisms in presumed infectious endophthalmitis using Next generation sequencing (NGS) was carried out in vitreous biopsies from 34 patients with endophthalmitis, and thirty patients undergoing surgery for non-infectious retinal disorders as controls. Following DNA extraction using the Qiagen mini kit and PCR amplification of the V3-V4 regions of...

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PMID: 30696908
DOI: 10.1038/s41598-018-37502-w

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