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Article

Mesenchymal stem cells in psoriatic lesions affect the skin microenvironment through circular RNA

21 Jan 2019

Abstract excerpt

Psoriasis is an autoimmune skin disease. Our previous studies revealed abnormal immune regulation of skin mesenchymal stem cells (S-MSCs) in psoriatic lesions. Circular RNA (circRNA) molecules were recently discovered as a new class of non-coding regulatory RNAs. Their role in the pathogenesis of psoriasis has not yet been studied. To explore potential circRNA-mediated mechanisms of S-MSCs in the pathogenesis of...

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PMID: 30664808
DOI: 10.1111/exd.13890

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