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Article

DHHC protein family targets different subsets of glioma stem cells in specific niches

18 Jan 2019

Abstract excerpt

BACKGROUND: Glioblastomas (GBM) comprise different subsets that exhibit marked heterogeneity and plasticity, leading to a lack of success of genomic profiling in guiding the development of precision medicine approaches against these tumors. Accordingly, there is an urgent need to investigate the regulatory mechanisms for different GBM subsets and identify novel biomarkers and therapeutic targets relevant in the...

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PMID: 30658672
DOI: 10.1186/s13046-019-1033-2

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