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Physical Determinants of Amyloid Assembly in Biofilm Formation

7 Jan 2019

Abstract excerpt

Biofilms are generated by bacteria, embedded in the formed extracellular matrix. The biofilm's function is to improve the survival of a bacterial colony through, for example, increased resistance to antibiotics or other environmental stresses. Proteins secreted by the bacteria act as a major structural component of this extracellular matrix, as they self-assemble into highly stable amyloid fibrils, making the...

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PMID: 30622185
DOI: 10.1128/mbio.02279-18

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