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Neonatal gut colonization byStaphylococcus aureusstrains with certain adhesins and superantigens is negatively associated with subsequent development of atopic eczema

26 Nov 2018

Abstract excerpt

BACKGROUND: Insufficient early immune stimulation may predispose to atopic disease. Staphylococcus aureus, a skin and gut colonizer, produces the B-cell mitogen protein A and T-cell-activating superantigens. Early gut colonization by S. aureus strains that possess the superantigens encoded by the enterotoxin gene (egc) cluster and elastin-binding protein is negatively associated with development of atopic eczema....

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PMID: 30474111
DOI: 10.1111/bjd.17451

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