Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Highly Pathogenic Clone of Shiga Toxin–ProducingEscherichia coliO157:H7, England and Wales

5 Nov 2018

Abstract excerpt

We used whole-genome sequencing to investigate the evolutionary context of an emerging highly pathogenic strain of Shiga toxin-producing Escherichia coli (STEC) O157:H7 in England and Wales. A timed phylogeny of sublineage IIb revealed that the emerging clone evolved from a STEC O157:H7 stx-negative ancestor ≈10 years ago after acquisition of a bacteriophage encoding Shiga toxin (stx) 2a, which in turn had...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteriophages and microbial interactions
Share to Escherichia coli research studies
Share to Viral gastroenteritis research and epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30457532
DOI: 10.3201/eid2412.180409

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Highly Pathogenic Clone of Shiga Toxin–ProducingEscherichia coliO157:H7, England and WalesPMID 30457532Read ↗

Comparison of Shiga toxin-encoding bacteriophages in highly pathogenic strains of Shiga toxin-producing Escherichia coli O157:H7 in the UKSemantic proximity Read ↗

Applying phylogenomics to understand the emergence of Shiga-toxin-producing Escherichia coli O157:H7 strains causing severe human disease in the UKSemantic proximity Read ↗

Multiple evolutionary trajectories for non-O157 Shiga toxigenic <i>Escherichia coli</i>Semantic proximity Read ↗

Stx-Phages: Drivers and Mediators of the Evolution of STEC and STEC-Like PathogensSemantic proximity Read ↗

Genotypic analysis of Shiga toxin-producing Escherichia coli clonal complex 17 in England and Wales, 2014-2022.Semantic proximity Read ↗

Temporal dynamics and acquisition of Shiga toxin subtype <i>stx2a</i> within Shiga toxin-producing <i>Escherichia coli</i> in England, 2016 – 2024Semantic proximity Read ↗

Pathogenomes and virulence profiles of representative big six non-O157 serogroup Shiga toxin-producing Escherichia coliSemantic proximity Read ↗

Evidence for Contemporary Switching of the O-Antigen Gene Cluster between Shiga Toxin-Producing Escherichia coli Strains Colonizing CattleSemantic proximity Read ↗

Investigation on the Evolution of Shiga Toxin-Converting Phages Based on Whole Genome SequencingSemantic proximity Read ↗

Identification of domestic reservoirs and common exposures in an emerging lineage of Shiga toxin-producing Escherichia coli O157:H7 in England: a genomic epidemiological analysisSemantic proximity Read ↗

Phylogenomic framework and virulence gene boundaries of emerging Shiga toxin-producing <i>Escherichia coli</i> O118 informed by the comprehensive profiling of 359 O118 genomesSemantic proximity Read ↗

Genomic Epidemiology of Shiga Toxin-Producing Escherichia coli Isolated from the Livestock-Food-Human Interface in South AmericaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.