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Article

Genomic updates in understanding PTSD.

Progress in neuro-psychopharmacology & biological psychiatry - 2 Mar 2019

Sharma Sumeet, Ressler Kerry J

Abstract excerpt

Twin studies as well as more recent genetics-based heritability analyses demonstrate that up to 40 to 50% of the variance in predicting PTSD following trauma is heritable. However, most of the specific gene pathways and mechanism that mediate risk vs. resilience for PTSD following trauma exposure have yet to be elucidated. This review will examine the latest results from large scale Genome-wide association...

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PMID: 30452941
DOI: 10.1016/j.pnpbp.2018.11.010
PMCID: PMC6431237

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