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Article

An NAD+-dependent novel transcription factor controls stage conversion in Entamoeba

29 Oct 2018

Abstract excerpt

Developmental switching between life-cycle stages is a common feature among parasitic pathogens to facilitate disease transmission and pathogenesis. The protozoan parasite Entamoeba switches between invasive trophozoites and dormant cysts, but the encystation process remains poorly understood despite being central to amoebic biology. We identify a transcription factor, Encystation Regulatory Motif-Binding Protein...

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PMID: 30375973
DOI: 10.7554/elife.37912

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