Article
TRPM2 SNP genotype previously associated with susceptibility to Rhodococcus equi pneumonia in Quarter Horse foals displays differential gene expression identified using RNA-Seq.
BMC genomics - 5 Dec 2016
McQueen Cole M, Whitfield-Cargile Canaan M, Konganti Kranti, Blodgett Glenn P, Dindot Scott V, Cohen Noah D
Abstract excerpt
BACKGROUND: Rhodococcus equi (R. equi) is an intracellular bacterium that affects young foals and immuno-compromised individuals causing severe pneumonia. Currently, the genetic mechanisms that confer susceptibility and/or resistance to R. equi are not fully understood. Previously, using a SNP-based genome-wide association study, we identified a region on equine chromosome 26 associated with culture-confirmed...
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