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Roles for osteocalcin in proliferation and differentiation of spermatogonial cells cocultured with somatic cells

9 Oct 2018

Abstract excerpt

Spermatogonial cells (SCs) are key cells for spermatogenesis. These cells are affected by paracrine signals originated from nearby somatic cells, among them Leydig cells have receptors for osteocalcin, a hormone known for exerting positive roles in the promotion of spermatogenesis. The aim of this study was to evaluate roles for osteocalcin on SCs proliferative and differentiation features after coculture with...

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PMID: 30302795
DOI: 10.1002/jcb.27767

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