Article
No difference in effectiveness of treatment simplification to boosted or unboosted atazanavir plus lamivudine in virologically suppressed in HIV-1-infected patients.
PloS one - 1 Jan 2018
Gutierrez-Valencia Alicia, García Coral, Viciana Pompeyo, Milanés-Guisado Yusnelkis, Fernandez-Magdaleno Tamara, Espinosa Nuria, Pasquau Juan, López-Cortés Luis Fernando
Abstract excerpt
BACKGROUND: Simplification strategies of antiretroviral treatment represent effective tools for the reduction of drug-induced toxicity, resistance mutations in case of virological failure and costs. OBJECTIVES: To assess the effectiveness of simplification to atazanavir/ritonavir (ATVrtv) or unboosted atazanavir (ATV400) plus lamivudine, and if low plasma or intracellular ATV Ctrough influence virological...
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