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Article

Exosomes from BM-MSCs increase the population of CSCs via transfer of miR-142-3p

1 Sept 2018

Abstract excerpt

BACKGROUND: Bone marrow-derived mesenchymal stem/stromal cells (BM-MSCs) are progenitor cells shown to migrate to the tumour and participate in the tumour microenvironment. BM-MSCs play important roles in tumour processes through the release of cytokines or exosomes; however, how BM-MSCs influence the stemness of CSCs in colon cancer cells remains poorly understood. METHODS: We isolated exosomes from BM-MSCs and...

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PMID: 30220706
DOI: 10.1038/s41416-018-0254-z

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