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Article

Aicardi goutières syndrome is associated with pulmonary hypertension.

Molecular genetics and metabolism - 1 Dec 2018

Adang Laura A, Frank David B, Gilani Ahmed, Takanohashi Asako, Ulrick Nicole, Collins Abigail, Cross Zachary, Galambos Csaba, Helman Guy, Kanaan Usama, Keller Stephanie, Simon Dawn, Sherbini Omar, Hanna Brian D, Vanderver Adeline L

Abstract excerpt

While pulmonary hypertension (PH) is a potentially life threatening complication of many inflammatory conditions, an association between Aicardi Goutières syndrome (AGS), a rare genetic cause of interferon (IFN) overproduction, and the development of PH has not been characterized to date. We analyzed the cardiac function of individuals with AGS enrolled in the Myelin Disorders Bioregistry Project using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypertension, Pulmonary

Share to Infant, Newborn

Share to Interferon-Induced Helicase, IFIH1

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Source

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Identifiers

PMID: 30219631
DOI: 10.1016/j.ymgme.2018.09.004
PMCID: PMC6880931

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